What is the 4 hour rule after Botox?
The aftercare rule every injector repeats — and what it actually protects.
In the Chicago area, 20 units of Botox typically costs $200–$400, based on the going local rate of $10–$20 per unit. Twenty units is the usual first dose for frown lines. Northwest Indiana injectors tend to land near the lower end of that range, while downtown Chicago and North Shore practices price toward the top.
Updated June 2026 · Local pricing data · No paid placements
Botox is priced per unit, so the only honest way to compare quotes is to ask two questions: what’s the per-unit price, and how many units am I getting? Around Chicagoland and Northwest Indiana, $10–$20 a unit is typical — which is why 20 units lands at roughly $200–$400. Be wary of flat “per area” pricing that hides the math: 15 units at a bargain headline price can cost more per unit than 20 units somewhere reputable.
Keep in mind that 20 units usually covers one area — most often the frown lines between the brows. Treating forehead lines often adds another 10–20 units, and crow’s feet typically take 12–24, so a full upper face costs noticeably more than that first $200–$400 visit. What moves the price beyond unit count? Mostly who’s holding the syringe — an MD or NP generally charges more than an RN working under medical direction — plus the venue and the neighborhood. Gold Coast rent shows up in Gold Coast pricing, which is part of why NWI often comes in lower.
One budgeting note a good injector will volunteer: results last about 3–4 months, so most regulars book three to four visits a year. Think in annual terms — a $300 visit is really a $900–$1,200-a-year habit — and the cheapest quote matters a lot less than consistent, careful work.
The aftercare rule every injector repeats — and what it actually protects.
Filler longevity works very differently from Botox — here’s the range.
Comparing budgets? Microneedling is priced per session, not per unit.
Pricing, safety, aftercare, and where to go across Chicago & NWI.
This guide is for information only — it isn’t medical advice. Always confirm credentials and suitability at your consult.